The Knowledge Project with Shane Parrish

• #217 Josh Wolfe: Human Advantage in the World of AI

  While Silicon Valley chases unicorns, Josh Wolfe hunts for something far more elusive: scientific breakthroughs that could change civilization. As co-founder and managing partner of Lux Capital, he's looking for the kind of science that turns impossible into inevitable. Josh doesn’t just invest in the future—he sees it coming before almost anyone else.    In this conversation, we explore:  The rapid evolution of AI and potential bottlenecks slowing its growth  The geopolitical battle for technological dominance and rise of sovereign AI models  How advances in automation, robotics, and defence are shifting global power dynamics  Josh's unfiltered thoughts on Tesla and Elon Musk  AI's revolution of medical research  Parenting in a tech-dominated world  How AI is forcing us to rethink creativity, intellectual property, and human intelligence itself  Why the greatest risk isn't AI itself—but our ability to separate truth from noise    Despite the challenges ahead, Josh remains profoundly optimistic about human potential. He believes technology isn't replacing what makes us human—it's amplifying it. This episode will challenge how you think about innovation, risk, and the forces shaping our future. If you want to stay ahead of the curve, you can't afford to miss it.    Josh Wolfe co-founded Lux Capital to support scientists and entrepreneurs who pursue counter-conventional solutions to the most vexing puzzles of our time. He previously worked in investment banking at Salomon Smith Barney and in capital markets at Merrill Lynch. Josh is a columnist with Forbes and Editor for the Forbes/Wolfe Emerging Tech Report.  (00:00:00) Introduction (00:02:46) Current Obsessions (00:05:11) AI and its Limitations (00:10:58) Memory Players in AI (00:13:27) Human Intelligence as a Limiting Factor (00:15:38) Disruption in Elite Professions (00:17:15) AI and Blue-Collar Jobs (00:18:29) Implications of AI in Coding (00:19:40) AI and Company Margins (00:25:48) AI in Pharma (00:26:44) AI in Entertainment (00:28:04) AI in Scientific Research (00:33:31) AI in Patent Creation (00:34:49) AI in Company Creation (00:35:33) Discussion on Tesla and Elon Musk (00:40:54) AI in Investment Decisions (00:42:20) AI in Analyzing Business Fundamentals (00:45:27) AI, Privacy, and Information Gods (00:53:04) AI and Art (00:56:43) AI and Human Connection (00:58:22) AI, Aging, and Memory (01:00:46) The Impact of Remote Work on Social Dynamics (01:03:18) The Role of Community and Belonging (01:05:44) The Pursuit of Longevity (01:11:58) The Importance of Family and Purpose (01:14:18) Information Processing and Workflow (01:26:03) Investment in Military Technology (01:28:09) Global Conflict and Military Deterrence (01:31:28) Information Warfare (01:32:32) Infiltration and Weaponization of Systems (01:37:06) Infrastructure Maintenance and Growth (01:38:27) DOGE Initiative (01:40:09) Attracting Capital and Global Competitiveness (01:43:16) Attracting Talent and Immigration (01:45:42) Designing a System from Scratch (01:47:30) AI and Intellectual Property (01:51:56) The Fear of AI   Newsletter - The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter Upgrade — If you want to hear my thoughts and reflections at the end of the episode, join our membership: ⁠⁠⁠⁠⁠⁠⁠fs.blog/membership⁠⁠ and get your own private feed. Watch on YouTube: @tkppodcast Learn more about your ad choices. Visit megaphone.fm/adchoices

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• #216 Outliers: Andrew Mellon – America’s Secret Banker

  He was the strangest titan America ever produced: a whisper-quiet banker who turned systematic thinking into a superpower, building an industrial empire while barely raising his voice above a murmur. Andrew Mellon's story isn't just about money—it's about how patience, observation, and positioning can create more wealth than charisma ever could. But when the Great Depression hit, the very qualities that made him rich made him the perfect villain for a nation demanding change.  Whether you're building a business, investing in the future, or seeking insights on strategic decision-making, Mellon's story reveals the power of patience, positioning, and playing the long game.  (2:25) Prologue: The Quiet Titan (4:20) Part 1 - The Judge's Son (6:36) Benjamin Franklin's Blueprint (8:53) The Pittsburgh Promise (10:45) Andrew's Early Years (13:11) Part 2 - Building the System (14:23) The Banking Foundation (17:09) Panic Creates Opportunity (20:09) Andy at the Wheel (22:05) Opportunity in Aluminum (24:10) The Mellon System (27:12) Connections Create Power (29:02) Reinvesting Success (30:51) Staying in the Shadows (33:28) Part 3 - The Private Kingdom (34:52) A Broken Heart (36:56) Science Meets Industry (39:35) Preparations for War (41:39) The Silent Empire Strikes (44:04) Part 4 - Washington's Banker (45:58) The Banker Takes Command (47:49) The Banker's Paradox (50:27) The Silent Man Learns to Speak (52:03) Part 5 - The Fall (53:56) 1928 (55:25) Black Thursday (57:23) When Strength Becomes Weakness (59:58) Roosevelt's Vendetta (1:02:48) The Silent Man Shouted Down (1:05:01) The Final Battle: Mellon's Tax Trial (1:09:04) The End of an Era (1:10:14) Epilogue - The Final Gift (1:11:44) Thinking Long Term This podcast is for information purposes only and draws primarily from two foundational books: David Cannadine's 'Mellon: An American Life', the first comprehensive published biography of Andrew W. Mellon, which masterfully chronicles his journey from shy Pittsburgh boy to industrial titan, Treasury Secretary, and philanthropist. The second source, 'Thomas Mellon and His Times', written by Andrew's father Thomas Mellon himself provides invaluable firsthand insights into the immigrant experience and the formation of the Mellon family's business philosophy in America. If this story captured your interest, we highly recommend both works – Cannadine's for its thorough examination of Andrew's profound impact on American business, politics, and philanthropy, and Thomas Mellon's autobiography for its intimate portrait of the family's rise from immigrant farmers to financial powerhouses in both nineteenth- and twentieth-century Pittsburgh.  Upgrade — If you want to hear my thoughts and reflections at the end of the episode, join our membership: ⁠⁠⁠⁠⁠⁠⁠fs.blog/membership⁠⁠ and get your own private feed. Newsletter - The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

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• #215 David Heacock: Managing and Marketing a $250M Business

  Imagine leaving a six‐figure Wall Street salary behind to chase a single, daring idea. In this episode, David Heacock shows you how he turned a basic product into a $250M empire. At 29, he left Wall Street to bet on air filters. That bet transformed into Filterbuy, now a $250 million direct-to-consumer manufacturer serving more than 7 million customers through a ruthlessly efficient operation. Today we talk about what actually matters when building a business, balancing obsession with family life, selling on Amazon, what he’d do differently if starting over, and the freight decision he calls his biggest mistake. Whether you’re starting a business, scaling one, or simply looking for insights on hiring, managing, or making bold decisions, David shares the lessons that helped him build his empire.    David Heacock is the founder and CEO of Filterbuy. Before revolutionizing the air filter industry, he traded options at Goldman Sachs from 2005-2012.  If you’re driven by bold decisions and value hard-won lessons, this conversation is your playbook. Don’t miss out on the insights that could redefine your own path to success. Newsletter - The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter Upgrade — If you want to hear my thoughts and reflections at the end of the episode, join our membership: ⁠⁠⁠⁠⁠⁠⁠fs.blog/membership⁠⁠ and get your own private feed. Watch on YouTube: @tkppodcast (00:02:56) David's Journey to Goldman Sachs  (00:06:07) Committing to Entrepreneurship  (00:07:35) The Power of Obsession  (00:10:08) The Decision to Expand Geographically  (00:12:55) Challenges in Building the First Plant  (00:18:58) Management Level Hiring  (00:22:41) Studying Operating Systems for Companies  (00:24:49) The Nuances of Hiring  (00:25:53) External Accountability  (00:29:37) Adapting Business Operating Systems  (00:30:13) The Role of a Chief of Staff  (00:31:03) Building Department-Specific Operating Models  (00:32:56) Articulating the Company's Mission and Values  (00:44:19) Understanding Marketing and Branding  (00:47:10) The Strategy Behind Intent-Based Marketing  (00:52:13) The Decision to Enter Retail  (00:57:26) Success in Retail and Customer Acquisition  (00:58:19) Diversifying Market Segments  (00:59:13) Competitive Advantage Over Other Brands  (01:01:07) The Logistics Aspect of the Business  (01:04:25) Defining Direct-to-Consumer Brands  (01:08:39) Technical Challenges and Overcoming Setbacks  (01:11:46) Core Personal Traits for Success  (01:16:37) The Power of Obsession Over Willpower  (01:17:46) Facing the Hardest Moments in Business  (01:26:36) The Decision to Enter the Freight Business  (01:30:48) Diversifying into the HVAC Service Business  (01:34:51) The Future of HVAC Service Business  (01:36:01) Personal Branding and Business Growth  (01:37:23) The Role of Marketing and Operations  (01:38:48) Contrasting Business Models: Private Equity  (01:43:00) The Importance of Mission and Vision  (01:47:12) Balancing Obsession and Family Life  (01:53:44) The Dangers of Lifestyle Creep and Maintaining Financial Stability  Learn more about your ad choices. Visit megaphone.fm/adchoices

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  2:02:30
• #214 Outliers: Timothy Eaton and The Original ‘Everything Store’

  So far with The Knowledge Project Podcast, we've focused on interviews. But I’ve learned as much from reading biographies as from interviewing amazing people. That’s why we’re starting 'Lessons from Outliers.' Every other week, we'll study an outlier who did remarkable work. From industrialists who reimagined commerce to the irreverent personalities who challenged the foundations of their fields, we'll explore what they did and how they did it. We can learn something from everyone.     We're starting Outliers with Timothy Eaton, a Canadian name that might not be familiar to many listeners today, but his innovations fundamentally changed retail and how we shop. This episode is about how he built that empire, the principles that drove its success, and the forces that eventually brought it all crashing down. Whether you're building a business, leading a team, or trying to understand how great companies rise and fall, Timothy Eaton's story offers timeless lessons about innovation, trust, and the true price of success. You'll learn why even the mightiest empires can crumble when they forget the principles that built them and why success—no matter how massive—must be earned and re-earned daily.  (01:55) Introduction (05:04) The Vision (06:16) Timothy’s Early Years (09:28) The System (12:17) The Innovation Engine (14:18) The Scale Game (18:08) The Platform Play (19:32) The Leadership Philosophy (20:48) The Succession (22:21) Retail as Entertainment (23:14) The Western Expansion (25:12) Building the National Network (26:05) Creating the Corporate Family (26:43) The Pinnacle of Power (27:43) The Inherited Crown (28:33) The Comfortable Plateau (31:33) The Weight of Tradition (33:12) The Profit Paradox (34:02) The Identity Crisis (34:51) The Final Chapter This podcast is for information purposes only and draws primarily from two excellent books: ‘The Eatons: The Rise and Fall of Canada's Royal Family’ by Rod McQueen which chronicles the Eaton family history and the company’s journey from beginning to end, and ‘Timothy Eaton and the Rise of His Department Store’ by Joy L. Santiuk, which focuses on the founder’s life. If this story captured your interest, we highly recommend both books for their thorough documentation of what became a Canadian institution for over a century.  Newsletter - The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter Upgrade — If you want to hear my thoughts and reflections at the end of the episode, join our membership: ⁠⁠⁠⁠⁠⁠⁠fs.blog/membership⁠⁠ and get your own private feed. Learn more about your ad choices. Visit megaphone.fm/adchoices

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  42:07
• #213 Mickey Drexler: The Art of Selling with Retail's Merchant Prince

  This episode will transform how you think about style, aspiration, and the art of knowing what people want before they know it themselves. From working in department stores to advising Steve Jobs on Apple’s retail strategy when it didn’t have retail at all, Drexler’s career traces the evolution of American retail itself: from local shops to mall dominance, from catalog to digital, from mass market to personalization. Whether you’re an aspiring entrepreneur, a retail enthusiast, or someone looking to build a brand that stands the test of time, Mickey shares invaluable insights on what separates truly successful brands from the rest. Mickey Drexler is the chairman of Alex Mill. Before that, he was the CEO of J. Crew and sat on the Board of Directors of Apple. He founded Old Navy and Madewell, and served as the CEO of Gap from 1983–2002. Learn why gaining real-world insights—and not just reports or data—is crucial to staying ahead of the competition. Newsletter - The Brain Food newsletter delivers actionable insights and thoughtful ideas every Sunday. It takes 5 minutes to read, and it’s completely free. Learn more and sign up at fs.blog/newsletter Upgrade — If you want to hear my thoughts and reflections at the end of the episode, join our membership: ⁠⁠⁠⁠⁠⁠⁠fs.blog/membership⁠⁠ and get your own private feed. Watch on YouTube: @tkppodcast (02:16) How Mickey Drexler became Mickey Drexler (07:04) Lessons from redefining Gap (12:47) Merchant, defined (15:17) How Drexler evaluates stores (19:20) Lessons from running Gap (21:19) On Old Navy (27:26) On Steve Jobs and Working with Apple (33:00) Re-making J. Crew (37:00) Drexler's superpower (43:40) Current-day retailers who are great (45:10) How Drexler got "Madewell" (47:15) What makes something a classic look? (50:20) On success Learn more about your ad choices. Visit megaphone.fm/adchoices

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